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 This study consisted of the determination of the trace metals and some physiochemical properties in drinking water samples from the Brong Ahafo region of the Republic of Ghana، where drinking water samples are not treated before it is consumed. The purpose was to ascertain the quality of water from these sources. Samples were taken from fifteen sampling points and analyzed for the following parameters Fe، Cu، Mn، Zn، Al، NO3-، NO2-، SO42-، PO42-، and F- using the procedure outline in the Palintest Photometer Method. The data showed the variation of the investigated parameters in samples as follows: pH 5.57-7.54، conductivity (EC) 35-1216 µs/cm، turbidity 3.25-72.50 NTU، PO42- 1 0.32-9.30 mg/L، F- 0.32-1.05 mg/L، NO3- 0.09-0.99 mg/L، NO2- 0.006-0.114 mg/L، SO42- 3.33-8.02 mg/L، Cu 1.19-2.75 mg/L Fe 0.05-0.85mg/L، Zn 0.04-0.15 mg/L، Mn 0.003-0.011 mg/L and Al 0.05-0.15 mg/L. The concentrations of most of the investigated parameters in the drinking water samples from Brong Ahafo region were within the permissible limits of the World Health Organization drinking water quality guidelines. There were no correlations between metal concentrations in the drinking water samples.